diff --git a/crates/bevy_core_pipeline/src/upscaling/mod.rs b/crates/bevy_core_pipeline/src/upscaling/mod.rs
index 4ce91de393..37ae95e3cb 100644
--- a/crates/bevy_core_pipeline/src/upscaling/mod.rs
+++ b/crates/bevy_core_pipeline/src/upscaling/mod.rs
@@ -42,6 +42,7 @@ fn prepare_view_upscaling_pipelines(
     mut pipelines: ResMut<SpecializedRenderPipelines<BlitPipeline>>,
     blit_pipeline: Res<BlitPipeline>,
     view_targets: Query<(Entity, &ViewTarget, Option<&ExtractedCamera>)>,
+    persistent_pipeline_cache: Option<Res<PersistentPipelineCache>>,
 ) {
     let mut output_textures = <HashSet<_>>::default();
     for (entity, view_target, camera) in view_targets.iter() {
@@ -81,7 +82,7 @@ fn prepare_view_upscaling_pipelines(
         let pipeline = pipelines.specialize(&pipeline_cache, &blit_pipeline, key);
 
         // Ensure the pipeline is loaded before continuing the frame to prevent frames without any GPU work submitted
-        pipeline_cache.block_on_render_pipeline(pipeline);
+        pipeline_cache.block_on_render_pipeline(pipeline, persistent_pipeline_cache.as_deref());
 
         commands
             .entity(entity)
diff --git a/crates/bevy_render/src/render_resource/mod.rs b/crates/bevy_render/src/render_resource/mod.rs
index f156b0ecb0..cc8ec94f87 100644
--- a/crates/bevy_render/src/render_resource/mod.rs
+++ b/crates/bevy_render/src/render_resource/mod.rs
@@ -7,6 +7,7 @@ mod bindless;
 mod buffer;
 mod buffer_vec;
 mod gpu_array_buffer;
+mod persistent_pipeline_cache;
 mod pipeline;
 mod pipeline_cache;
 mod pipeline_specializer;
@@ -25,6 +26,7 @@ pub use bindless::*;
 pub use buffer::*;
 pub use buffer_vec::*;
 pub use gpu_array_buffer::*;
+pub use persistent_pipeline_cache::*;
 pub use pipeline::*;
 pub use pipeline_cache::*;
 pub use pipeline_specializer::*;
diff --git a/crates/bevy_render/src/render_resource/persistent_pipeline_cache.rs b/crates/bevy_render/src/render_resource/persistent_pipeline_cache.rs
new file mode 100644
index 0000000000..bca4aa4d81
--- /dev/null
+++ b/crates/bevy_render/src/render_resource/persistent_pipeline_cache.rs
@@ -0,0 +1,346 @@
+use crate::{renderer::RenderAdapterInfo, ExtractSchedule, RenderSystems};
+use alloc::sync::Arc;
+use bevy_app::{App, Plugin};
+use bevy_ecs::{
+    change_detection::{Res, ResMut},
+    error::BevyError,
+    prelude::{not, resource_exists, IntoScheduleConfigs},
+    resource::Resource,
+    system::{Commands, Local},
+};
+use bevy_platform::hash::FixedHasher;
+use bevy_render::{render_resource::PipelineCache, renderer::RenderDevice, Extract, Render};
+use bevy_utils::WgpuWrapper;
+use core::hash::BuildHasher;
+use std::{
+    fs,
+    fs::OpenOptions,
+    io,
+    io::Write,
+    path::{Path, PathBuf},
+    sync::Mutex,
+    thread::JoinHandle,
+};
+use thiserror::Error;
+use tracing::{debug, warn};
+use wgpu::{hal::PipelineCacheError, Backend, PipelineCacheDescriptor};
+
+/// Plugin for managing [`wgpu::PipelineCache`] resources across application runs.
+///
+/// When pipelines are compiled by [`crate::PipelineCache`], if this plugin is enabled, it will
+/// persist the pipeline cache to disk, allowing for faster startup times in subsequent runs.
+///
+/// Note: This plugin is currently only supported on the Vulkan backend.
+pub struct PersistentPipelineCachePlugin {
+    /// A unique key for the application, used to identify the cache directory. Should change
+    /// if the application is updated or if the cache should be invalidated.
+    pub application_key: &'static str,
+    /// The directory where the pipeline cache will be stored.
+    pub data_dir: PathBuf,
+    /// The eviction policy for the cache.
+    pub eviction_policy: EvictionPolicy,
+}
+
+impl PersistentPipelineCachePlugin {
+    /// Creates a new instance of the `PersistentPipelineCachePlugin` with the specified
+    /// application key.
+    pub fn new(application_key: &'static str, data_dir: PathBuf) -> Self {
+        Self {
+            application_key,
+            data_dir,
+            eviction_policy: EvictionPolicy::Never,
+        }
+    }
+}
+
+impl Plugin for PersistentPipelineCachePlugin {
+    fn build(&self, _app: &mut App) {}
+
+    fn finish(&self, app: &mut App) {
+        if !self.data_dir.exists() || !self.data_dir.is_dir() {
+            warn!(
+                "PersistentPipelineCachePlugin data directory does not exist or is not a directory: {:?}",
+                self.data_dir
+            );
+            return;
+        }
+
+        if let Some(render_app) = app.get_sub_app_mut(bevy_render::RenderApp) {
+            let adapter_debug = render_app.world().resource::<RenderAdapterInfo>();
+            if adapter_debug.backend != Backend::Vulkan {
+                warn!("PersistentPipelineCachePlugin is only supported on Vulkan backend..");
+                return;
+            }
+            render_app
+                .add_systems(
+                    ExtractSchedule,
+                    extract_persistent_pipeline_cache
+                        .run_if(not(resource_exists::<PersistentPipelineCache>)),
+                )
+                .add_systems(
+                    Render,
+                    write_persistent_pipeline_cache
+                        .run_if(resource_exists::<PersistentPipelineCache>)
+                        .in_set(RenderSystems::Cleanup),
+                );
+        };
+
+        app.insert_resource(PersistentPipelineCacheConfig {
+            application_key: self.application_key,
+            data_dir: self.data_dir.clone(),
+            eviction_policy: self.eviction_policy,
+        });
+    }
+}
+
+pub fn extract_persistent_pipeline_cache(
+    mut commands: Commands,
+    persistent_pipeline_cache_config: Extract<Option<Res<PersistentPipelineCacheConfig>>>,
+    adapter_debug: Res<RenderAdapterInfo>,
+    render_device: Res<RenderDevice>,
+) -> Result<(), BevyError> {
+    let Some(persistent_pipeline_cache_config) = &*persistent_pipeline_cache_config else {
+        return Ok(());
+    };
+
+    debug!(
+        "Extracting persistent pipeline cache with application key: {}",
+        persistent_pipeline_cache_config.application_key
+    );
+    let cache_path = persistent_pipeline_cache_config
+        .data_dir
+        .join(persistent_pipeline_cache_config.application_key);
+
+    match persistent_pipeline_cache_config.eviction_policy {
+        EvictionPolicy::Always => {
+            // Evict all existing data
+            if cache_path.exists() {
+                fs::remove_dir_all(&cache_path).map_err(PersistentPipelineCacheError::Io)?;
+            }
+        }
+        EvictionPolicy::Stale => {
+            // Evict all but matching our application key
+            if cache_path.exists() {
+                for entry in fs::read_dir(&cache_path).map_err(PersistentPipelineCacheError::Io)? {
+                    // Check if the entry is a directory and doesn't match the cache path
+                    let entry = entry.map_err(PersistentPipelineCacheError::Io)?;
+                    if entry
+                        .file_type()
+                        .map_err(PersistentPipelineCacheError::Io)?
+                        .is_dir()
+                        && entry.file_name() != cache_path
+                    {
+                        fs::remove_dir_all(entry.path())
+                            .map_err(PersistentPipelineCacheError::Io)?;
+                        debug!("Evicted stale pipeline cache at {:?}", entry.path());
+                    }
+                }
+            }
+        }
+        EvictionPolicy::Never => {}
+    }
+
+    let cache_key = wgpu::util::pipeline_cache_key(&adapter_debug)
+        .ok_or(PersistentPipelineCacheError::InvalidAdapterKey)?;
+    let cache_path = cache_path.join(cache_key);
+
+    // Ensure the cache directory exists
+    if let Some(parent) = cache_path.parent() {
+        if !parent.exists() {
+            debug!(
+                "Creating persistent pipeline cache directory at {:?}",
+                parent
+            );
+            fs::create_dir_all(parent).map_err(PersistentPipelineCacheError::Io)?;
+        }
+    }
+
+    let persistent_pipeline_cache = PersistentPipelineCache::new(
+        &render_device,
+        persistent_pipeline_cache_config.application_key,
+        &cache_path,
+    )?;
+
+    commands.insert_resource(persistent_pipeline_cache);
+    Ok(())
+}
+
+pub fn write_persistent_pipeline_cache(
+    mut persistent_pipeline_cache: ResMut<PersistentPipelineCache>,
+    pipeline_cache: Res<PipelineCache>,
+    mut pipeline_cache_size: Local<usize>,
+) -> Result<(), BevyError> {
+    let cache_size = pipeline_cache.size();
+    if cache_size > *pipeline_cache_size {
+        persistent_pipeline_cache.write()?;
+        *pipeline_cache_size = cache_size;
+    }
+
+    Ok(())
+}
+
+/// Configuration for the persistent pipeline cache.
+#[derive(Resource)]
+pub struct PersistentPipelineCacheConfig {
+    /// A unique key for the application, used to identify the cache directory.
+    pub application_key: &'static str,
+    /// The directory where the pipeline cache will be stored.
+    pub data_dir: PathBuf,
+    /// The eviction policy for the cache.
+    pub eviction_policy: EvictionPolicy,
+}
+
+/// Resource for managing [`wgpu::PipelineCache`].
+#[derive(Resource)]
+pub struct PersistentPipelineCache {
+    cache: Arc<WgpuWrapper<wgpu::PipelineCache>>,
+    write_lock: Arc<Mutex<()>>,
+    write_tasks: Vec<JoinHandle<Result<(), PersistentPipelineCacheError>>>,
+    cache_path: PathBuf,
+    data_key: u64,
+}
+
+impl PersistentPipelineCache {
+    /// Create a new instance of the persistent pipeline cache with the given application key and
+    /// cache path.
+    pub fn new(
+        render_device: &RenderDevice,
+        app_key: &'static str,
+        cache_path: &Path,
+    ) -> Result<Self, PersistentPipelineCacheError> {
+        // Get data if the cache file exists
+        let cache_data = if cache_path.exists() {
+            let data = fs::read(cache_path).map_err(PersistentPipelineCacheError::Io)?;
+            debug!(
+                "Loaded persistent pipeline cache from {:?}, size: {}",
+                cache_path,
+                data.len()
+            );
+            Some(data)
+        } else {
+            debug!("Creating new persistent pipeline cache at {:?}", cache_path);
+            None
+        };
+        // SAFETY: Data was created with a cache key that matches the adapter.
+        let cache = unsafe {
+            render_device
+                .wgpu_device()
+                .create_pipeline_cache(&PipelineCacheDescriptor {
+                    data: cache_data.as_deref(),
+                    label: app_key.into(),
+                    fallback: true,
+                })
+        };
+
+        let data_key = {
+            let hasher = FixedHasher;
+            hasher.hash_one(&cache_data)
+        };
+
+        Ok(PersistentPipelineCache {
+            cache: Arc::new(WgpuWrapper::new(cache)),
+            write_lock: Arc::new(Mutex::new(())),
+            write_tasks: vec![],
+            cache_path: cache_path.to_path_buf(),
+            data_key,
+        })
+    }
+
+    /// Get the cached data if it has changed since the last call.
+    pub fn get_data(&mut self) -> Option<Vec<u8>> {
+        let data = self.cache.get_data();
+        let hasher = FixedHasher;
+        let data_key = hasher.hash_one(&data);
+        if self.data_key != data_key {
+            self.data_key = data_key;
+            return data;
+        }
+
+        None
+    }
+
+    /// Write the cached data to disk, if it has changed since the last write.
+    pub fn write(&mut self) -> Result<(), PersistentPipelineCacheError> {
+        // Process existing tasks
+        let mut pending_tasks = vec![];
+        let mut error = None;
+        for task in self.write_tasks.drain(..) {
+            if task.is_finished() {
+                match task.join() {
+                    Ok(Ok(())) => {
+                        debug!("Persistent pipeline cache write task completed successfully.");
+                    }
+                    Ok(Err(err)) => {
+                        warn!("Persistent pipeline cache write task failed: {}", err);
+                        error = Some(err);
+                    }
+                    Err(err) => {
+                        warn!("Persistent pipeline cache write task panicked: {:?}", err);
+                        error = Some(PersistentPipelineCacheError::Io(io::Error::other(
+                            "Persistent pipeline cache write task panicked",
+                        )));
+                    }
+                }
+            } else {
+                pending_tasks.push(task);
+            }
+        }
+
+        if let Some(err) = error {
+            return Err(err);
+        }
+
+        if let Some(data) = self.get_data() {
+            let temp = self.cache_path.with_extension("tmp");
+            let cache_path = self.cache_path.clone();
+            let lock = self.write_lock.clone();
+            let join_handle = std::thread::spawn(move || {
+                let _guard = lock
+                    .lock()
+                    .or(Err(PersistentPipelineCacheError::LockError))?;
+                let mut file = OpenOptions::new()
+                    .write(true)
+                    .create_new(true)
+                    .open(&temp)
+                    .map_err(PersistentPipelineCacheError::Io)?;
+                file.write_all(&data)
+                    .map_err(PersistentPipelineCacheError::Io)?;
+                fs::rename(&temp, &cache_path).map_err(PersistentPipelineCacheError::Io)?;
+                Ok(())
+            });
+            self.write_tasks.push(join_handle);
+        }
+
+        Ok(())
+    }
+
+    /// Get the underlying wgpu pipeline cache.
+    pub fn get_cache(&self) -> Arc<WgpuWrapper<wgpu::PipelineCache>> {
+        self.cache.clone()
+    }
+}
+
+/// Describes the eviction policy for the persistent pipeline cache.
+#[derive(Debug, Copy, Clone)]
+pub enum EvictionPolicy {
+    /// Evict all existing data on startup.
+    Always,
+    /// Evict all but the data matching the application key on startup.
+    Stale,
+    /// Never evict any data.
+    Never,
+}
+
+/// Error type for persistent pipeline cache operations.
+#[derive(Debug, Error)]
+#[error("Error while handling persistent pipeline cache")]
+pub enum PersistentPipelineCacheError {
+    #[error(transparent)]
+    Io(#[from] io::Error),
+    #[error("Failed to create pipeline cache: {0}")]
+    DeviceError(#[from] PipelineCacheError),
+    #[error("Could not create cache key from adapter")]
+    InvalidAdapterKey,
+    #[error("Failed to acquire write lock for persistent pipeline cache")]
+    LockError,
+}
diff --git a/crates/bevy_render/src/render_resource/pipeline_cache.rs b/crates/bevy_render/src/render_resource/pipeline_cache.rs
index 328c5e5600..a1474f6e8f 100644
--- a/crates/bevy_render/src/render_resource/pipeline_cache.rs
+++ b/crates/bevy_render/src/render_resource/pipeline_cache.rs
@@ -1,3 +1,4 @@
+use crate::render_resource::persistent_pipeline_cache::PersistentPipelineCache;
 use crate::{
     render_resource::*,
     renderer::{RenderAdapter, RenderDevice},
@@ -695,9 +696,13 @@ impl PipelineCache {
 
     /// Wait for a render pipeline to finish compiling.
     #[inline]
-    pub fn block_on_render_pipeline(&mut self, id: CachedRenderPipelineId) {
+    pub fn block_on_render_pipeline(
+        &mut self,
+        id: CachedRenderPipelineId,
+        persistent_cache: Option<&PersistentPipelineCache>,
+    ) {
         if self.pipelines.len() <= id.0 {
-            self.process_queue();
+            self.process_queue(persistent_cache);
         }
 
         let state = &mut self.pipelines[id.0].state;
@@ -807,10 +812,12 @@ impl PipelineCache {
         &mut self,
         id: CachedPipelineId,
         descriptor: RenderPipelineDescriptor,
+        persistent_cache: Option<&PersistentPipelineCache>,
     ) -> CachedPipelineState {
         let device = self.device.clone();
         let shader_cache = self.shader_cache.clone();
         let layout_cache = self.layout_cache.clone();
+        let cache = persistent_cache.map(PersistentPipelineCache::get_cache);
 
         create_pipeline_task(
             async move {
@@ -903,7 +910,7 @@ impl PipelineCache {
                             // TODO: Should this be the same as the vertex compilation options?
                             compilation_options,
                         }),
-                    cache: None,
+                    cache: cache.as_deref().map(|v| &**v),
                 };
 
                 Ok(Pipeline::RenderPipeline(
@@ -918,10 +925,12 @@ impl PipelineCache {
         &mut self,
         id: CachedPipelineId,
         descriptor: ComputePipelineDescriptor,
+        persistent_cache: Option<&PersistentPipelineCache>,
     ) -> CachedPipelineState {
         let device = self.device.clone();
         let shader_cache = self.shader_cache.clone();
         let layout_cache = self.layout_cache.clone();
+        let cache = persistent_cache.map(PersistentPipelineCache::get_cache);
 
         create_pipeline_task(
             async move {
@@ -962,7 +971,7 @@ impl PipelineCache {
                         zero_initialize_workgroup_memory: descriptor
                             .zero_initialize_workgroup_memory,
                     },
-                    cache: None,
+                    cache: cache.as_deref().map(|v| &**v),
                 };
 
                 Ok(Pipeline::ComputePipeline(
@@ -979,7 +988,7 @@ impl PipelineCache {
     /// be called manually to force creation at a different time.
     ///
     /// [`RenderSystems::Render`]: crate::RenderSystems::Render
-    pub fn process_queue(&mut self) {
+    pub fn process_queue(&mut self, persistent_cache: Option<&PersistentPipelineCache>) {
         let mut waiting_pipelines = mem::take(&mut self.waiting_pipelines);
         let mut pipelines = mem::take(&mut self.pipelines);
 
@@ -996,22 +1005,26 @@ impl PipelineCache {
         }
 
         for id in waiting_pipelines {
-            self.process_pipeline(&mut pipelines[id], id);
+            self.process_pipeline(&mut pipelines[id], id, persistent_cache);
         }
 
         self.pipelines = pipelines;
     }
 
-    fn process_pipeline(&mut self, cached_pipeline: &mut CachedPipeline, id: usize) {
+    fn process_pipeline(
+        &mut self,
+        cached_pipeline: &mut CachedPipeline,
+        id: usize,
+        persistent_cache: Option<&PersistentPipelineCache>,
+    ) {
         match &mut cached_pipeline.state {
             CachedPipelineState::Queued => {
                 cached_pipeline.state = match &cached_pipeline.descriptor {
                     PipelineDescriptor::RenderPipelineDescriptor(descriptor) => {
-                        self.start_create_render_pipeline(id, *descriptor.clone())
-                    }
-                    PipelineDescriptor::ComputePipelineDescriptor(descriptor) => {
-                        self.start_create_compute_pipeline(id, *descriptor.clone())
+                        self.start_create_render_pipeline(id, *descriptor.clone(), persistent_cache)
                     }
+                    PipelineDescriptor::ComputePipelineDescriptor(descriptor) => self
+                        .start_create_compute_pipeline(id, *descriptor.clone(), persistent_cache),
                 };
             }
 
@@ -1051,8 +1064,11 @@ impl PipelineCache {
         self.waiting_pipelines.insert(id);
     }
 
-    pub(crate) fn process_pipeline_queue_system(mut cache: ResMut<Self>) {
-        cache.process_queue();
+    pub(crate) fn process_pipeline_queue_system(
+        mut cache: ResMut<Self>,
+        persistent_pipeline_cache: Option<Res<PersistentPipelineCache>>,
+    ) {
+        cache.process_queue(persistent_pipeline_cache.as_deref());
     }
 
     pub(crate) fn extract_shaders(
@@ -1080,6 +1096,10 @@ impl PipelineCache {
             }
         }
     }
+
+    pub fn size(&self) -> usize {
+        self.pipelines.len()
+    }
 }
 
 #[cfg(all(